P682-1396 Screening compound: N-(4-ethylphenyl)-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

P682-1396 Screening compound: N-(4-ethylphenyl)-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide
P682-1396 Screening compound: N-(4-ethylphenyl)-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P682-1396
N-(4-ethylphenyl)-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P682-1396

Molecular Formula

C23H18FN3O3 (C23 H18 FN3 O3)

Compound Name

N-(4-ethylphenyl)-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

IUPAC name

N-(4-ethylphenyl)-1-(3-fluorophenyl)-4-hydroxy-2-oxo-12-dihydro-18-naphthyridine-3-carboxamide

SMILES

CCc(cc1)ccc1NC(C(C(N(c1cccc(F)c1)c1ncccc11)=O)=C1O)=O

InChI

InChI=1S/C23H18FN3O3/c1-2-14-8-10-16(11-9-14)26-22(29)19-20(28)18-7-4-12-25-21(18)27(23(19)30)17-6-3-5-15(24)13-17/h3-13,28H,2H2,1H3,(H,26,29)

InChI Key

PJRKHCUYAHGHIH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27611947

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.623

Distribution Coefficient, logD

-1.002

Water Solubility, LogSw

-3.76

Polar Surface Area

63.223

Acid Dissociation Constant (pKa)

2.78

Base Dissociation Constant (pKb)

-1.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

P682-1396 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P682-1396 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P682-1396?
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What is the minimum amount of P682-1396 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P682-1396
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P682-1396
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P682-1396 available by request