P682-1437 Screening compound: N-(4-ethylphenyl)-4-hydroxy-1-(3-methoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

P682-1437 Screening compound: N-(4-ethylphenyl)-4-hydroxy-1-(3-methoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide
P682-1437 Screening compound: N-(4-ethylphenyl)-4-hydroxy-1-(3-methoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P682-1437
N-(4-ethylphenyl)-4-hydroxy-1-(3-methoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P682-1437

Molecular Formula

C24H21N3O4 (C24 H21 N3 O4)

Compound Name

N-(4-ethylphenyl)-4-hydroxy-1-(3-methoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

IUPAC name

N-(4-ethylphenyl)-4-hydroxy-1-(3-methoxyphenyl)-2-oxo-12-dihydro-18-naphthyridine-3-carboxamide

SMILES

CCc(cc1)ccc1NC(C(C(N(c1cc(OC)ccc1)c1ncccc11)=O)=C1O)=O

InChI

InChI=1S/C24H21N3O4/c1-3-15-9-11-16(12-10-15)26-23(29)20-21(28)19-8-5-13-25-22(19)27(24(20)30)17-6-4-7-18(14-17)31-2/h4-14,28H,3H2,1-2H3,(H,26,29)

InChI Key

VNEYWVYAFHKZAN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27611980

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.711

Distribution Coefficient, logD

-0.913

Water Solubility, LogSw

-3.88

Polar Surface Area

70.767

Acid Dissociation Constant (pKa)

2.78

Base Dissociation Constant (pKb)

-1.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

P682-1437 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P682-1437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P682-1437?
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What is the minimum amount of P682-1437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P682-1437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P682-1437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P682-1437 available by request