P708-0544 Screening compound: 1-[4-(3-ethyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-carboxamide

P708-0544 Screening compound: 1-[4-(3-ethyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-carboxamide
P708-0544 Screening compound: 1-[4-(3-ethyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P708-0544
1-[4-(3-ethyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P708-0544

Molecular Formula

C19H18N6O2S (C19 H18 N6 O2 S)

Compound Name

1-[4-(3-ethyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-carboxamide

IUPAC name

1-[4-(3-ethyl-124-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-N-[(thiophen-2-yl)methyl]-1H-pyrazole-4-carboxamide

SMILES

CCc1noc(-c2cc(-n3ncc(C(NCc4cccs4)=O)c3C)ncc2)n1

InChI

InChI=1S/C19H18N6O2S/c1-3-16-23-19(27-24-16)13-6-7-20-17(9-13)25-12(2)15(11-22-25)18(26)21-10-14-5-4-8-28-14/h4-9,11H,3,10H2,1-2H3,(H,21,26)

InChI Key

AKKJZMLLRPGUNE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27613229

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.671

Distribution Coefficient, logD

3.671

Water Solubility, LogSw

-3.80

Polar Surface Area

80.914

Acid Dissociation Constant (pKa)

12.63

Base Dissociation Constant (pKb)

2.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

P708-0544 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

GPCR Targeted Library (31838 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P708-0544 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P708-0544?
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What is the minimum amount of P708-0544 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P708-0544
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P708-0544
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P708-0544 available by request