P709-0277 Screening compound: 1-{5-methyl-1-[5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-1H-pyrazole-4-carbonyl}-4-(pyridin-2-yl)piperazine

P709-0277 Screening compound: 1-{5-methyl-1-[5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-1H-pyrazole-4-carbonyl}-4-(pyridin-2-yl)piperazine
P709-0277 Screening compound: 1-{5-methyl-1-[5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-1H-pyrazole-4-carbonyl}-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P709-0277
1-{5-methyl-1-[5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-1H-pyrazole-4-carbonyl}-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P709-0277

Molecular Formula

C22H22N8O2 (C22 H22 N8 O2)

Compound Name

1-{5-methyl-1-[5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-1H-pyrazole-4-carbonyl}-4-(pyridin-2-yl)piperazine

IUPAC name

1-{5-methyl-1-[5-(3-methyl-124-oxadiazol-5-yl)pyridin-2-yl]-1H-pyrazole-4-carbonyl}-4-(pyridin-2-yl)piperazine

SMILES

Cc(n(-c(cc1)ncc1-c1nc(C)no1)nc1)c1C(N(CC1)CCN1c1ncccc1)=O

InChI

InChI=1S/C22H22N8O2/c1-15-18(22(31)29-11-9-28(10-12-29)19-5-3-4-8-23-19)14-25-30(15)20-7-6-17(13-24-20)21-26-16(2)27-32-21/h3-8,13-14H,9-12H2,1-2H3

InChI Key

QYNVUQDCMWKWGA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27613391

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.527

Distribution Coefficient, logD

2.518

Water Solubility, LogSw

-2.57

Polar Surface Area

82.614

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

P709-0277 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with P709-0277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P709-0277?
Check Price and Availability of P709-0277, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P709-0277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P709-0277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P709-0277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P709-0277 available by request