P709-0905 Screening compound: 2-{1-[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-1H-pyrazole-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline

P709-0905 Screening compound: 2-{1-[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-1H-pyrazole-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline
P709-0905 Screening compound: 2-{1-[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-1H-pyrazole-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound P709-0905
2-{1-[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-1H-pyrazole-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P709-0905

Molecular Formula

C24H22N6O2 (C24 H22 N6 O2)

Compound Name

2-{1-[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-1H-pyrazole-4-carbonyl}-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-{1-[5-(3-cyclopropyl-124-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-1H-pyrazole-4-carbonyl}-1234-tetrahydroisoquinoline

SMILES

Cc(n(-c(cc1)ncc1-c1nc(C2CC2)no1)nc1)c1C(N(CC1)Cc2c1cccc2)=O

InChI

InChI=1S/C24H22N6O2/c1-15-20(24(31)29-11-10-16-4-2-3-5-19(16)14-29)13-26-30(15)21-9-8-18(12-25-21)23-27-22(28-32-23)17-6-7-17/h2-5,8-9,12-13,17H,6-7,10-11,14H2,1H3

InChI Key

LTPDNVYXLOTJIU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27613474

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.161

Distribution Coefficient, logD

4.159

Water Solubility, LogSw

-4.09

Polar Surface Area

71.143

Acid Dissociation Constant (pKa)

24.26

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

P709-0905 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P709-0905 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P709-0905?
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What is the minimum amount of P709-0905 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P709-0905
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P709-0905
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P709-0905 available by request