P725-0100 Screening compound: 1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-2-(3-methylphenoxy)ethan-1-one

P725-0100 Screening compound: 1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-2-(3-methylphenoxy)ethan-1-one
P725-0100 Screening compound: 1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-2-(3-methylphenoxy)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P725-0100
1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-2-(3-methylphenoxy)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P725-0100

Molecular Formula

C21H20N2O2S (C21 H20 N2 O2 S)

Compound Name

1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-2-(3-methylphenoxy)ethan-1-one

IUPAC name

1-[5-(2-methyl-13-thiazol-4-yl)-23-dihydro-1H-indol-1-yl]-2-(3-methylphenoxy)ethan-1-one

SMILES

Cc1nc(-c(cc2)cc(CC3)c2N3C(COc2cc(C)ccc2)=O)cs1

InChI

InChI=1S/C21H20N2O2S/c1-14-4-3-5-18(10-14)25-12-21(24)23-9-8-17-11-16(6-7-20(17)23)19-13-26-15(2)22-19/h3-7,10-11,13H,8-9,12H2,1-2H3

InChI Key

ABXSOXZVLGEOIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27614097

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.670

Distribution Coefficient, logD

4.670

Water Solubility, LogSw

-4.49

Polar Surface Area

32.429

Acid Dissociation Constant (pKa)

23.39

Base Dissociation Constant (pKb)

1.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

P725-0100 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P725-0100 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P725-0100?
Check Price and Availability of P725-0100, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P725-0100 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P725-0100
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P725-0100
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P725-0100 available by request