P725-0248 Screening compound: 1-(2-chloropyridine-4-carbonyl)-5-(2-cyclopropyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indole

P725-0248 Screening compound: 1-(2-chloropyridine-4-carbonyl)-5-(2-cyclopropyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indole
P725-0248 Screening compound: 1-(2-chloropyridine-4-carbonyl)-5-(2-cyclopropyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound P725-0248
1-(2-chloropyridine-4-carbonyl)-5-(2-cyclopropyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P725-0248

Molecular Formula

C20H16ClN3OS (C20 H16 ClN3 OS)

Compound Name

1-(2-chloropyridine-4-carbonyl)-5-(2-cyclopropyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indole

IUPAC name

1-(2-chloropyridine-4-carbonyl)-5-(2-cyclopropyl-13-thiazol-4-yl)-23-dihydro-1H-indole

SMILES

O=C(c1cc(Cl)ncc1)N(CC1)c(cc2)c1cc2-c1csc(C2CC2)n1

InChI

InChI=1S/C20H16ClN3OS/c21-18-10-15(5-7-22-18)20(25)24-8-6-14-9-13(3-4-17(14)24)16-11-26-19(23-16)12-1-2-12/h3-5,7,9-12H,1-2,6,8H2

InChI Key

PJDPGLUCWCEGRS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27614116

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.89

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.379

Distribution Coefficient, logD

4.379

Water Solubility, LogSw

-4.60

Polar Surface Area

34.818

Acid Dissociation Constant (pKa)

23.73

Base Dissociation Constant (pKb)

3.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

P725-0248 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
  • 3D
  • Fragments
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P725-0248 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P725-0248?
Check Price and Availability of P725-0248, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P725-0248 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P725-0248
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P725-0248
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P725-0248 available by request