P725-0262 Screening compound: 5-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)-1-(PYRIDINE-4-CARBONYL)-2,3-DIHYDRO-1H-INDOLE

P725-0262 Screening compound: 5-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)-1-(PYRIDINE-4-CARBONYL)-2,3-DIHYDRO-1H-INDOLE
P725-0262 Screening compound: 5-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)-1-(PYRIDINE-4-CARBONYL)-2,3-DIHYDRO-1H-INDOLE alternative view

Chemical Structure Depiction of ChemDiv screening compound P725-0262
5-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)-1-(PYRIDINE-4-CARBONYL)-2,3-DIHYDRO-1H-INDOLE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P725-0262

Molecular Formula

C20H17N3OS (C20 H17 N3 OS)

Compound Name

5-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)-1-(PYRIDINE-4-CARBONYL)-2,3-DIHYDRO-1H-INDOLE

IUPAC name

n/a

SMILES

O=C(c1ccncc1)N(CC1)c(cc2)c1cc2-c1csc(C2CC2)n1

InChI

InChI=1S/C20H17N3OS/c24-20(14-5-8-21-9-6-14)23-10-7-16-11-15(3-4-18(16)23)17-12-25-19(22-17)13-1-2-13/h3-6,8-9,11-13H,1-2,7,10H2

InChI Key

YJSWOZXOEXHDKX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27614125

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

347.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.622

Distribution Coefficient, logD

3.622

Water Solubility, LogSw

-3.78

Polar Surface Area

35.331

Acid Dissociation Constant (pKa)

23.73

Base Dissociation Constant (pKb)

3.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

P725-0262 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with P725-0262 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P725-0262?
Check Price and Availability of P725-0262, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P725-0262 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P725-0262
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P725-0262
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P725-0262 available by request