P734-1842 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-8-methoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide

P734-1842 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-8-methoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide
P734-1842 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-8-methoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P734-1842
N-[(2-chloro-4-fluorophenyl)methyl]-8-methoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P734-1842

Molecular Formula

C18H18ClFN2O3 (C18 H18 ClFN2 O3)

Compound Name

N-[(2-chloro-4-fluorophenyl)methyl]-8-methoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide

IUPAC name

N-[(2-chloro-4-fluorophenyl)methyl]-8-methoxy-6-oxo-2346-tetrahydro-1H-quinolizine-9-carboxamide

SMILES

COC(C(C(NCc(ccc(F)c1)c1Cl)=O)=C1N2CCCC1)=CC2=O

InChI

InChI=1S/C18H18ClFN2O3/c1-25-15-9-16(23)22-7-3-2-4-14(22)17(15)18(24)21-10-11-5-6-12(20)8-13(11)19/h5-6,8-9H,2-4,7,10H2,1H3,(H,21,24)

InChI Key

MXQOZUNCYDCLPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28998922

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.8

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.395

Distribution Coefficient, logD

2.019

Water Solubility, LogSw

-3.37

Polar Surface Area

48.648

Acid Dissociation Constant (pKa)

7.26

Base Dissociation Constant (pKb)

-2.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P734-1842 in Drug Discovery

Included in Screening Libraries

Ligand-Gated Ion Channels Library (3887 compounds)

Protein-Protein Interaction Library (218420 compounds)

STING Agonist Library (5895 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Cancer
  • Immune system
  • Cancer
Targets:
  • Ion Channels
  • Others
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P734-1842 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P734-1842?
Check Price and Availability of P734-1842, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P734-1842 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P734-1842
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P734-1842
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P734-1842 available by request