P734-1981 Screening compound: 8-methoxy-6-oxo-N-(5,6,7,8-tetrahydronaphthalen-1-yl)-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide

P734-1981 Screening compound: 8-methoxy-6-oxo-N-(5,6,7,8-tetrahydronaphthalen-1-yl)-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide
P734-1981 Screening compound: 8-methoxy-6-oxo-N-(5,6,7,8-tetrahydronaphthalen-1-yl)-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P734-1981
8-methoxy-6-oxo-N-(5,6,7,8-tetrahydronaphthalen-1-yl)-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P734-1981

Molecular Formula

C21H24N2O3 (C21 H24 N2 O3)

Compound Name

8-methoxy-6-oxo-N-(5,6,7,8-tetrahydronaphthalen-1-yl)-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxamide

IUPAC name

8-methoxy-6-oxo-N-(5678-tetrahydronaphthalen-1-yl)-2346-tetrahydro-1H-quinolizine-9-carboxamide

SMILES

COC(C(C(Nc1c(CCCC2)c2ccc1)=O)=C1N2CCCC1)=CC2=O

InChI

InChI=1S/C21H24N2O3/c1-26-18-13-19(24)23-12-5-4-11-17(23)20(18)21(25)22-16-10-6-8-14-7-2-3-9-15(14)16/h6,8,10,13H,2-5,7,9,11-12H2,1H3,(H,22,25)

InChI Key

XWPUVDABDRUKJB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996994

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.906

Distribution Coefficient, logD

2.695

Water Solubility, LogSw

-3.41

Polar Surface Area

46.548

Acid Dissociation Constant (pKa)

7.60

Base Dissociation Constant (pKb)

-2.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

P734-1981 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Anti-HIV1 Library (19540 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Nervous system
  • Eye
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Cancer
Targets:
  • GPCR
  • Ion Channels
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with P734-1981 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P734-1981?
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What is the minimum amount of P734-1981 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P734-1981
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P734-1981
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P734-1981 available by request