P734-2251 Screening compound: ethyl 3-(8-ethoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-amido)benzoate

P734-2251 Screening compound: ethyl 3-(8-ethoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-amido)benzoate
P734-2251 Screening compound: ethyl 3-(8-ethoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-amido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound P734-2251
ethyl 3-(8-ethoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-amido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P734-2251

Molecular Formula

C21H24N2O5 (C21 H24 N2 O5)

Compound Name

ethyl 3-(8-ethoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-amido)benzoate

IUPAC name

ethyl 3-(8-ethoxy-6-oxo-2346-tetrahydro-1H-quinolizine-9-amido)benzoate

SMILES

CCOC(c1cccc(NC(C(C(OCC)=C2)=C(CCCC3)N3C2=O)=O)c1)=O

InChI

InChI=1S/C21H24N2O5/c1-3-27-17-13-18(24)23-11-6-5-10-16(23)19(17)20(25)22-15-9-7-8-14(12-15)21(26)28-4-2/h7-9,12-13H,3-6,10-11H2,1-2H3,(H,22,25)

InChI Key

NMQCMZDXRHWLJJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28997085

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.212

Distribution Coefficient, logD

2.366

Water Solubility, LogSw

-3.42

Polar Surface Area

67.659

Acid Dissociation Constant (pKa)

6.62

Base Dissociation Constant (pKb)

-0.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

P734-2251 in Drug Discovery

Included in Screening Libraries

Ligand-Gated Ion Channels Library (3887 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Cancer
Targets:
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P734-2251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P734-2251?
Check Price and Availability of P734-2251, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P734-2251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P734-2251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P734-2251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P734-2251 available by request