P757-0069 Screening compound: 1-(2,5-dimethylphenyl)-4-{7-methylpyrazolo[1,5-a]pyrimidine-5-carbonyl}piperazine

P757-0069 Screening compound: 1-(2,5-dimethylphenyl)-4-{7-methylpyrazolo[1,5-a]pyrimidine-5-carbonyl}piperazine
P757-0069 Screening compound: 1-(2,5-dimethylphenyl)-4-{7-methylpyrazolo[1,5-a]pyrimidine-5-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P757-0069
1-(2,5-dimethylphenyl)-4-{7-methylpyrazolo[1,5-a]pyrimidine-5-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P757-0069

Molecular Formula

C20H23N5O (C20 H23 N5 O)

Compound Name

1-(2,5-dimethylphenyl)-4-{7-methylpyrazolo[1,5-a]pyrimidine-5-carbonyl}piperazine

IUPAC name

1-(25-dimethylphenyl)-4-{7-methylpyrazolo[15-a]pyrimidine-5-carbonyl}piperazine

SMILES

Cc1cc(N(CC2)CCN2C(c2nc3ccnn3c(C)c2)=O)c(C)cc1

InChI

InChI=1S/C20H23N5O/c1-14-4-5-15(2)18(12-14)23-8-10-24(11-9-23)20(26)17-13-16(3)25-19(22-17)6-7-21-25/h4-7,12-13H,8-11H2,1-3H3

InChI Key

ULFZOACKMQCXDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27614223

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.140

Distribution Coefficient, logD

3.140

Water Solubility, LogSw

-2.99

Polar Surface Area

39.382

Acid Dissociation Constant (pKa)

26.40

Base Dissociation Constant (pKb)

2.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

P757-0069 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P757-0069 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P757-0069?
Check Price and Availability of P757-0069, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P757-0069 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P757-0069
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P757-0069
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P757-0069 available by request