P759-1083 Screening compound: morpholino[5-(3-pyridylmethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl]methanone

P759-1083 Screening compound: morpholino[5-(3-pyridylmethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl]methanone
P759-1083 Screening compound: morpholino[5-(3-pyridylmethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P759-1083
morpholino[5-(3-pyridylmethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P759-1083

Molecular Formula

C17H21N5O2 (C17 H21 N5 O2)

Compound Name

morpholino[5-(3-pyridylmethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl]methanone

IUPAC name

4-{5-[(pyridin-3-yl)methyl]-2H4H5H6H7H-pyrazolo[43-c]pyridine-3-carbonyl}morpholine

SMILES

O=C(c1c(CN(Cc2cnccc2)CC2)c2n[nH]1)N1CCOCC1

InChI

InChI=1S/C17H21N5O2/c23-17(22-6-8-24-9-7-22)16-14-12-21(5-3-15(14)19-20-16)11-13-2-1-4-18-10-13/h1-2,4,10H,3,5-9,11-12H2,(H,19,20)

InChI Key

HCJUTVFFKYUXAB-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

327.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

-0.221

Distribution Coefficient, logD

-5.409

Water Solubility, LogSw

-0.95

Polar Surface Area

62.740

Acid Dissociation Constant (pKa)

11.48

Base Dissociation Constant (pKb)

9.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.06

P759-1083 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with P759-1083 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P759-1083?
Check Price and Availability of P759-1083, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P759-1083 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P759-1083
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P759-1083
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P759-1083 available by request