P759-1394 Screening compound: 5-(2,5-difluorobenzoyl)-N~3~,N~3~-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide

P759-1394 Screening compound: 5-(2,5-difluorobenzoyl)-N~3~,N~3~-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide
P759-1394 Screening compound: 5-(2,5-difluorobenzoyl)-N~3~,N~3~-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P759-1394
5-(2,5-difluorobenzoyl)-N~3~,N~3~-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P759-1394

Molecular Formula

C16H16F2N4O2 (C16 H16 F2 N4 O2)

Compound Name

5-(2,5-difluorobenzoyl)-N~3~,N~3~-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide

IUPAC name

5-(25-difluorobenzoyl)-NN-dimethyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-3-carboxamide

SMILES

CN(C)C(c1n[nH]c(CC2)c1CN2C(c(cc(cc1)F)c1F)=O)=O

InChI

InChI=1S/C16H16F2N4O2/c1-21(2)16(24)14-11-8-22(6-5-13(11)19-20-14)15(23)10-7-9(17)3-4-12(10)18/h3-4,7H,5-6,8H2,1-2H3,(H,19,20)

InChI Key

OPKKLTGAOIWKIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29001177

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

334.33

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.634

Distribution Coefficient, logD

0.634

Water Solubility, LogSw

-2.30

Polar Surface Area

57.582

Acid Dissociation Constant (pKa)

7.37

Base Dissociation Constant (pKb)

-0.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.25

P759-1394 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

Bromodomain Modulators Library (5801 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Hemic and lymphatic
  • Nervous system
  • Eye
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
Targets:
  • Ion Channels
  • GPCR
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P759-1394 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P759-1394?
Check Price and Availability of P759-1394, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P759-1394 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P759-1394
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P759-1394
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P759-1394 available by request