P759-4952 Screening compound: 5-(2-bromobenzoyl)-N-(1-methylpiperidin-4-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide

P759-4952 Screening compound: 5-(2-bromobenzoyl)-N-(1-methylpiperidin-4-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide
P759-4952 Screening compound: 5-(2-bromobenzoyl)-N-(1-methylpiperidin-4-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P759-4952
5-(2-bromobenzoyl)-N-(1-methylpiperidin-4-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P759-4952

Molecular Formula

C20H24BrN5O2 (C20 H24 BrN5 O2)

Compound Name

5-(2-bromobenzoyl)-N-(1-methylpiperidin-4-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide

IUPAC name

5-(2-bromobenzoyl)-N-(1-methylpiperidin-4-yl)-1H4H5H6H7H-pyrazolo[43-c]pyridine-3-carboxamide

SMILES

CN(CC1)CCC1NC(c1n[nH]c(CC2)c1CN2C(c(cccc1)c1Br)=O)=O

InChI

InChI=1S/C20H24BrN5O2/c1-25-9-6-13(7-10-25)22-19(27)18-15-12-26(11-8-17(15)23-24-18)20(28)14-4-2-3-5-16(14)21/h2-5,13H,6-12H2,1H3,(H,22,27)(H,23,24)

InChI Key

WPOGMNGEZZFUIN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29002994

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.35

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.865

Distribution Coefficient, logD

-1.553

Water Solubility, LogSw

-2.35

Polar Surface Area

69.196

Acid Dissociation Constant (pKa)

7.19

Base Dissociation Constant (pKb)

9.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

P759-4952 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

Bromodomain Modulators Library (5801 compounds)

GPCR Targeted Library (31838 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Hemic and lymphatic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Eye
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Targets:
  • GPCR
  • Ion Channels
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P759-4952 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P759-4952?
Check Price and Availability of P759-4952, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P759-4952 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P759-4952
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P759-4952
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P759-4952 available by request