P804-0810 Screening compound: 1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-4-cyclohexanecarbonylpiperazine

P804-0810 Screening compound: 1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-4-cyclohexanecarbonylpiperazine
P804-0810 Screening compound: 1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-4-cyclohexanecarbonylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P804-0810
1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-4-cyclohexanecarbonylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P804-0810

Molecular Formula

C20H25ClN4O (C20 H25 ClN4 O)

Compound Name

1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-4-cyclohexanecarbonylpiperazine

IUPAC name

1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-4-cyclohexanecarbonylpiperazine

SMILES

O=C(C1CCCCC1)N(CC1)CCN1c1cc(-c(cc2)ccc2Cl)n[nH]1

InChI

InChI=1S/C20H25ClN4O/c21-17-8-6-15(7-9-17)18-14-19(23-22-18)24-10-12-25(13-11-24)20(26)16-4-2-1-3-5-16/h6-9,14,16H,1-5,10-13H2,(H,22,23)

InChI Key

LJMJKGUKWVWGEG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28041912

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.9

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.594

Distribution Coefficient, logD

4.594

Water Solubility, LogSw

-4.75

Polar Surface Area

42.292

Acid Dissociation Constant (pKa)

15.28

Base Dissociation Constant (pKb)

-0.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

P804-0810 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with P804-0810 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P804-0810?
Check Price and Availability of P804-0810, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P804-0810 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P804-0810
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P804-0810
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P804-0810 available by request