P805-0787 Screening compound: N-{1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-4-yl}-1H-indole-4-carboxamide

P805-0787 Screening compound: N-{1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-4-yl}-1H-indole-4-carboxamide
P805-0787 Screening compound: N-{1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-4-yl}-1H-indole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P805-0787
N-{1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-4-yl}-1H-indole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P805-0787

Molecular Formula

C23H22ClN5O (C23 H22 ClN5 O)

Compound Name

N-{1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-4-yl}-1H-indole-4-carboxamide

IUPAC name

N-{1-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-4-yl}-1H-indole-4-carboxamide

SMILES

O=C(c1c(cc[nH]2)c2ccc1)NC(CC1)CCN1c1cc(-c(cc2)ccc2Cl)n[nH]1

InChI

InChI=1S/C23H22ClN5O/c24-16-6-4-15(5-7-16)21-14-22(28-27-21)29-12-9-17(10-13-29)26-23(30)19-2-1-3-20-18(19)8-11-25-20/h1-8,11,14,17,25H,9-10,12-13H2,(H,26,30)(H,27,28)

InChI Key

AFYJWNAAPDFCKV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28042916

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.91

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.705

Distribution Coefficient, logD

4.705

Water Solubility, LogSw

-4.99

Polar Surface Area

59.372

Acid Dissociation Constant (pKa)

15.28

Base Dissociation Constant (pKb)

0.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

P805-0787 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

Bromodomain Modulators Library (5801 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Targets:
  • GPCR
Structure:
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with P805-0787 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P805-0787?
Check Price and Availability of P805-0787, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P805-0787 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P805-0787
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P805-0787
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P805-0787 available by request