P857-0202 Screening compound: N-[(4-fluorophenyl)methyl]-1-methyl-4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidine-6-carboxamide

P857-0202 Screening compound: N-[(4-fluorophenyl)methyl]-1-methyl-4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidine-6-carboxamide
P857-0202 Screening compound: N-[(4-fluorophenyl)methyl]-1-methyl-4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P857-0202
N-[(4-fluorophenyl)methyl]-1-methyl-4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P857-0202

Molecular Formula

C18H19FN6O2 (C18 H19 FN6 O2)

Compound Name

N-[(4-fluorophenyl)methyl]-1-methyl-4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidine-6-carboxamide

IUPAC name

N-[(4-fluorophenyl)methyl]-1-methyl-4-(morpholin-4-yl)-1H-pyrazolo[34-d]pyrimidine-6-carboxamide

SMILES

Cn1ncc2c(N3CCOCC3)nc(C(NCc(cc3)ccc3F)=O)nc12

InChI

InChI=1S/C18H19FN6O2/c1-24-16-14(11-21-24)17(25-6-8-27-9-7-25)23-15(22-16)18(26)20-10-12-2-4-13(19)5-3-12/h2-5,11H,6-10H2,1H3,(H,20,26)

InChI Key

JRHBCYPJIAYSDZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29026156

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.785

Distribution Coefficient, logD

1.785

Water Solubility, LogSw

-2.10

Polar Surface Area

69.365

Acid Dissociation Constant (pKa)

13.45

Base Dissociation Constant (pKb)

0.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P857-0202 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with P857-0202 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P857-0202?
Check Price and Availability of P857-0202, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P857-0202 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P857-0202
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P857-0202
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P857-0202 available by request