P861-1285 Screening compound: 5-[(2-methoxyethyl)amino]-3-methyl-6-phenyl-N-(propan-2-yl)imidazo[2,1-b][1,3]thiazole-2-carboxamide

P861-1285 Screening compound: 5-[(2-methoxyethyl)amino]-3-methyl-6-phenyl-N-(propan-2-yl)imidazo[2,1-b][1,3]thiazole-2-carboxamide
P861-1285 Screening compound: 5-[(2-methoxyethyl)amino]-3-methyl-6-phenyl-N-(propan-2-yl)imidazo[2,1-b][1,3]thiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P861-1285
5-[(2-methoxyethyl)amino]-3-methyl-6-phenyl-N-(propan-2-yl)imidazo[2,1-b][1,3]thiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P861-1285

Molecular Formula

C19H24N4O2S (C19 H24 N4 O2 S)

Compound Name

5-[(2-methoxyethyl)amino]-3-methyl-6-phenyl-N-(propan-2-yl)imidazo[2,1-b][1,3]thiazole-2-carboxamide

IUPAC name

5-[(2-methoxyethyl)amino]-3-methyl-6-phenyl-N-(propan-2-yl)imidazo[21-b][13]thiazole-2-carboxamide

SMILES

CC(C)NC(c(s1)c(C)n2c1nc(-c1ccccc1)c2NCCOC)=O

InChI

InChI=1S/C19H24N4O2S/c1-12(2)21-18(24)16-13(3)23-17(20-10-11-25-4)15(22-19(23)26-16)14-8-6-5-7-9-14/h5-9,12,20H,10-11H2,1-4H3,(H,21,24)

InChI Key

JOYYWFRSGTUTSG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27615730

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.271

Distribution Coefficient, logD

3.271

Water Solubility, LogSw

-3.50

Polar Surface Area

51.760

Acid Dissociation Constant (pKa)

14.34

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.84

P861-1285 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P861-1285 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P861-1285?
Check Price and Availability of P861-1285, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P861-1285 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P861-1285
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P861-1285
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P861-1285 available by request