P894-0144 Screening compound: 4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-N-{[4-(propan-2-yloxy)phenyl]methyl}phthalazin-1-amine

P894-0144 Screening compound: 4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-N-{[4-(propan-2-yloxy)phenyl]methyl}phthalazin-1-amine
P894-0144 Screening compound: 4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-N-{[4-(propan-2-yloxy)phenyl]methyl}phthalazin-1-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound P894-0144
4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-N-{[4-(propan-2-yloxy)phenyl]methyl}phthalazin-1-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P894-0144

Molecular Formula

C23H23N5O2 (C23 H23 N5 O2)

Compound Name

4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-N-{[4-(propan-2-yloxy)phenyl]methyl}phthalazin-1-amine

IUPAC name

4-(3-cyclopropyl-124-oxadiazol-5-yl)-N-{[4-(propan-2-yloxy)phenyl]methyl}phthalazin-1-amine

SMILES

CC(C)Oc1ccc(CNc2nnc(-c3nc(C4CC4)no3)c3ccccc23)cc1

InChI

InChI=1S/C23H23N5O2/c1-14(2)29-17-11-7-15(8-12-17)13-24-22-19-6-4-3-5-18(19)20(26-27-22)23-25-21(28-30-23)16-9-10-16/h3-8,11-12,14,16H,9-10,13H2,1-2H3,(H,24,27)

InChI Key

QHEDLEOPBATLFW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29026491

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.495

Distribution Coefficient, logD

4.486

Water Solubility, LogSw

-4.27

Polar Surface Area

72.086

Acid Dissociation Constant (pKa)

19.01

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

P894-0144 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P894-0144 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P894-0144?
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What is the minimum amount of P894-0144 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P894-0144
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P894-0144
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P894-0144 available by request