P906-1011 Screening compound: 4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-(1-ethyl-1H-pyrazole-3-carbonyl)-8-methyl-2,8-diazaspiro[4.5]decane

P906-1011 Screening compound: 4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-(1-ethyl-1H-pyrazole-3-carbonyl)-8-methyl-2,8-diazaspiro[4.5]decane
P906-1011 Screening compound: 4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-(1-ethyl-1H-pyrazole-3-carbonyl)-8-methyl-2,8-diazaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound P906-1011
4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-(1-ethyl-1H-pyrazole-3-carbonyl)-8-methyl-2,8-diazaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P906-1011

Molecular Formula

C20H28N6O2 (C20 H28 N6 O2)

Compound Name

4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-(1-ethyl-1H-pyrazole-3-carbonyl)-8-methyl-2,8-diazaspiro[4.5]decane

IUPAC name

4-(3-cyclopropyl-124-oxadiazol-5-yl)-2-(1-ethyl-1H-pyrazole-3-carbonyl)-8-methyl-28-diazaspiro[4.5]decane

SMILES

CCn(cc1)nc1C(N(C1)CC2(CCN(C)CC2)C1c1nc(C2CC2)no1)=O

InChI

InChI=1S/C20H28N6O2/c1-3-26-9-6-16(22-26)19(27)25-12-15(18-21-17(23-28-18)14-4-5-14)20(13-25)7-10-24(2)11-8-20/h6,9,14-15H,3-5,7-8,10-13H2,1-2H3/t15-/m0/s1

InChI Key

SINMNKQQLCHDBN-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD29028327

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.336

Distribution Coefficient, logD

-0.709

Water Solubility, LogSw

-1.93

Polar Surface Area

66.831

Acid Dissociation Constant (pKa)

24.36

Base Dissociation Constant (pKb)

9.44

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.00

P906-1011 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with P906-1011 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P906-1011?
Check Price and Availability of P906-1011, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P906-1011 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P906-1011
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P906-1011
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P906-1011 available by request