P909-2290 Screening compound: 5-{1-[(4-METHYL-1,3-THIAZOL-5-YL)METHYL]TETRAHYDRO-1H-PYRROL-3-YL}-3-PHENYL-1,2,4-OXADIAZOLE

P909-2290 Screening compound: 5-{1-[(4-METHYL-1,3-THIAZOL-5-YL)METHYL]TETRAHYDRO-1H-PYRROL-3-YL}-3-PHENYL-1,2,4-OXADIAZOLE
P909-2290 Screening compound: 5-{1-[(4-METHYL-1,3-THIAZOL-5-YL)METHYL]TETRAHYDRO-1H-PYRROL-3-YL}-3-PHENYL-1,2,4-OXADIAZOLE alternative view

Chemical Structure Depiction of ChemDiv screening compound P909-2290
5-{1-[(4-METHYL-1,3-THIAZOL-5-YL)METHYL]TETRAHYDRO-1H-PYRROL-3-YL}-3-PHENYL-1,2,4-OXADIAZOLE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P909-2290

Molecular Formula

C17H18N4OS (C17 H18 N4 OS)

Compound Name

5-{1-[(4-METHYL-1,3-THIAZOL-5-YL)METHYL]TETRAHYDRO-1H-PYRROL-3-YL}-3-PHENYL-1,2,4-OXADIAZOLE

IUPAC name

5-{1-[(4-methyl-13-thiazol-5-yl)methyl]pyrrolidin-3-yl}-3-phenyl-124-oxadiazole

SMILES

Cc1c(CN(CC2)CC2c2nc(-c3ccccc3)no2)scn1

InChI

InChI=1S/C17H18N4OS/c1-12-15(23-11-18-12)10-21-8-7-14(9-21)17-19-16(20-22-17)13-5-3-2-4-6-13/h2-6,11,14H,7-10H2,1H3/t14-/m1/s1

InChI Key

GQASUCRCWVLGDF-CQSZACIVSA-N

MDL Number (MFCD)

MFCD29031570

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.636

Distribution Coefficient, logD

2.230

Water Solubility, LogSw

-3.70

Polar Surface Area

45.881

Acid Dissociation Constant (pKa)

25.80

Base Dissociation Constant (pKb)

8.79

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.29

P909-2290 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • GPCR
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P909-2290 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P909-2290?
Check Price and Availability of P909-2290, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P909-2290 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P909-2290
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P909-2290
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P909-2290 available by request