P909-5448 Screening compound: 1-{3-METHYL-4-[3-(PYRIDIN-4-YL)-1,2,4-OXADIAZOL-5-YL]PYRROLIDIN-1-YL}-2-(PHENYLSULFANYL)ETHAN-1-ONE

P909-5448 Screening compound: 1-{3-METHYL-4-[3-(PYRIDIN-4-YL)-1,2,4-OXADIAZOL-5-YL]PYRROLIDIN-1-YL}-2-(PHENYLSULFANYL)ETHAN-1-ONE
P909-5448 Screening compound: 1-{3-METHYL-4-[3-(PYRIDIN-4-YL)-1,2,4-OXADIAZOL-5-YL]PYRROLIDIN-1-YL}-2-(PHENYLSULFANYL)ETHAN-1-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound P909-5448
1-{3-METHYL-4-[3-(PYRIDIN-4-YL)-1,2,4-OXADIAZOL-5-YL]PYRROLIDIN-1-YL}-2-(PHENYLSULFANYL)ETHAN-1-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P909-5448

Molecular Formula

C20H20N4O2S (C20 H20 N4 O2 S)

Compound Name

1-{3-METHYL-4-[3-(PYRIDIN-4-YL)-1,2,4-OXADIAZOL-5-YL]PYRROLIDIN-1-YL}-2-(PHENYLSULFANYL)ETHAN-1-ONE

IUPAC name

n/a

SMILES

C[C@@H](CN(C1)C(CSc2ccccc2)=O)[C@H]1c1nc(-c2ccncc2)no1

InChI

InChI=1S/C20H20N4O2S/c1-14-11-24(18(25)13-27-16-5-3-2-4-6-16)12-17(14)20-22-19(23-26-20)15-7-9-21-10-8-15/h2-10,14,17H,11-13H2,1H3/t14-,17-/m1/s1

InChI Key

VRDJHUIBASJJNK-RHSMWYFYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.487

Distribution Coefficient, logD

3.487

Water Solubility, LogSw

-3.73

Polar Surface Area

57.426

Acid Dissociation Constant (pKa)

24.48

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

30.00

P909-5448 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with P909-5448 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P909-5448?
Check Price and Availability of P909-5448, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P909-5448 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P909-5448
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P909-5448
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P909-5448 available by request