P932-0373 Screening compound: 1-[1-ethyl-3-(hydroxymethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-3-(1H-indol-3-yl)propan-1-one

P932-0373 Screening compound: 1-[1-ethyl-3-(hydroxymethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-3-(1H-indol-3-yl)propan-1-one
P932-0373 Screening compound: 1-[1-ethyl-3-(hydroxymethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-3-(1H-indol-3-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P932-0373
1-[1-ethyl-3-(hydroxymethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-3-(1H-indol-3-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P932-0373

Molecular Formula

C20H24N4O2 (C20 H24 N4 O2)

Compound Name

1-[1-ethyl-3-(hydroxymethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-3-(1H-indol-3-yl)propan-1-one

IUPAC name

1-[1-ethyl-3-(hydroxymethyl)-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl]-3-(1H-indol-3-yl)propan-1-one

SMILES

CCn1nc(CO)c(C2)c1CCN2C(CCc1c[nH]c2c1cccc2)=O

InChI

InChI=1S/C20H24N4O2/c1-2-24-19-9-10-23(12-16(19)18(13-25)22-24)20(26)8-7-14-11-21-17-6-4-3-5-15(14)17/h3-6,11,21,25H,2,7-10,12-13H2,1H3

InChI Key

PEPPIRBIZLJXEY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27616128

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.469

Distribution Coefficient, logD

1.469

Water Solubility, LogSw

-2.11

Polar Surface Area

57.959

Acid Dissociation Constant (pKa)

15.21

Base Dissociation Constant (pKb)

9.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

P932-0373 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Indole Derivatives (10091 compounds)

KRAS-Targeted Library (16000 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with P932-0373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P932-0373?
Check Price and Availability of P932-0373, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P932-0373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P932-0373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P932-0373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P932-0373 available by request