P950-0286 Screening compound: 1-[2-(4-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidin-8-yl]-2-(thiophen-3-yl)ethan-1-one

P950-0286 Screening compound: 1-[2-(4-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidin-8-yl]-2-(thiophen-3-yl)ethan-1-one
P950-0286 Screening compound: 1-[2-(4-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidin-8-yl]-2-(thiophen-3-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P950-0286
1-[2-(4-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidin-8-yl]-2-(thiophen-3-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P950-0286

Molecular Formula

C19H19N3O2S (C19 H19 N3 O2 S)

Compound Name

1-[2-(4-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidin-8-yl]-2-(thiophen-3-yl)ethan-1-one

IUPAC name

1-[2-(4-methoxyphenyl)-5H6H7H8H-imidazo[12-a]pyrimidin-8-yl]-2-(thiophen-3-yl)ethan-1-one

SMILES

COc(cc1)ccc1-c1cn(CCCN2C(Cc3cscc3)=O)c2n1

InChI

InChI=1S/C19H19N3O2S/c1-24-16-5-3-15(4-6-16)17-12-21-8-2-9-22(19(21)20-17)18(23)11-14-7-10-25-13-14/h3-7,10,12-13H,2,8-9,11H2,1H3

InChI Key

HSLUINHHBJNHPD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27616293

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.918

Distribution Coefficient, logD

3.918

Water Solubility, LogSw

-3.90

Polar Surface Area

34.916

Acid Dissociation Constant (pKa)

18.72

Base Dissociation Constant (pKb)

2.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.32

P950-0286 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with P950-0286 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P950-0286?
Check Price and Availability of P950-0286, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P950-0286 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P950-0286
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P950-0286
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P950-0286 available by request