P950-0344 Screening compound: 8-cyclobutanecarbonyl-2-(3-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine

P950-0344 Screening compound: 8-cyclobutanecarbonyl-2-(3-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine
P950-0344 Screening compound: 8-cyclobutanecarbonyl-2-(3-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P950-0344
8-cyclobutanecarbonyl-2-(3-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P950-0344

Molecular Formula

C18H21N3O2 (C18 H21 N3 O2)

Compound Name

8-cyclobutanecarbonyl-2-(3-methoxyphenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine

IUPAC name

8-cyclobutanecarbonyl-2-(3-methoxyphenyl)-5H6H7H8H-imidazo[12-a]pyrimidine

SMILES

COc1cccc(-c2cn(CCCN3C(C4CCC4)=O)c3n2)c1

InChI

InChI=1S/C18H21N3O2/c1-23-15-8-3-7-14(11-15)16-12-20-9-4-10-21(18(20)19-16)17(22)13-5-2-6-13/h3,7-8,11-13H,2,4-6,9-10H2,1H3

InChI Key

LTMUCUNVSIEGRT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27616302

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

311.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.903

Distribution Coefficient, logD

2.890

Water Solubility, LogSw

-2.96

Polar Surface Area

34.948

Acid Dissociation Constant (pKa)

23.28

Base Dissociation Constant (pKb)

5.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

P950-0344 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

GPCR Targeted Library (31838 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with P950-0344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P950-0344?
Check Price and Availability of P950-0344, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P950-0344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P950-0344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P950-0344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P950-0344 available by request