P950-2399 Screening compound: 3-[2-(2-fluorophenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine-8-carbonyl]-1,5-dimethyl-1H-pyrazole

P950-2399 Screening compound: 3-[2-(2-fluorophenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine-8-carbonyl]-1,5-dimethyl-1H-pyrazole
P950-2399 Screening compound: 3-[2-(2-fluorophenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine-8-carbonyl]-1,5-dimethyl-1H-pyrazole alternative view

Chemical Structure Depiction of ChemDiv screening compound P950-2399
3-[2-(2-fluorophenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine-8-carbonyl]-1,5-dimethyl-1H-pyrazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P950-2399

Molecular Formula

C18H18FN5O (C18 H18 FN5 O)

Compound Name

3-[2-(2-fluorophenyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrimidine-8-carbonyl]-1,5-dimethyl-1H-pyrazole

IUPAC name

3-[2-(2-fluorophenyl)-5H6H7H8H-imidazo[12-a]pyrimidine-8-carbonyl]-15-dimethyl-1H-pyrazole

SMILES

Cc1cc(C(N2c3nc(-c(cccc4)c4F)cn3CCC2)=O)nn1C

InChI

InChI=1S/C18H18FN5O/c1-12-10-15(21-22(12)2)17(25)24-9-5-8-23-11-16(20-18(23)24)13-6-3-4-7-14(13)19/h3-4,6-7,10-11H,5,8-9H2,1-2H3

InChI Key

UJFAJHOGNRLMFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27616369

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

339.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.219

Distribution Coefficient, logD

2.219

Water Solubility, LogSw

-2.73

Polar Surface Area

41.368

Acid Dissociation Constant (pKa)

22.50

Base Dissociation Constant (pKb)

3.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

P950-2399 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P950-2399 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P950-2399?
Check Price and Availability of P950-2399, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P950-2399 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P950-2399
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P950-2399
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P950-2399 available by request