R052-2673 Screening compound: 1H,4H-chromeno[4,3-c]pyrazole-3-carboxylic acid

R052-2673 Screening compound: 1H,4H-chromeno[4,3-c]pyrazole-3-carboxylic acid
R052-2673 Screening compound: 1H,4H-chromeno[4,3-c]pyrazole-3-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound R052-2673
1H,4H-chromeno[4,3-c]pyrazole-3-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

R052-2673

Molecular Formula

C11H8N2O3 (C11 H8 N2 O3)

Compound Name

1H,4H-chromeno[4,3-c]pyrazole-3-carboxylic acid

IUPAC name

1H4H-chromeno[43-c]pyrazole-3-carboxylic acid

SMILES

OC(c1n[nH]c-2c1COc1c2cccc1)=O

InChI

InChI=1S/C11H8N2O3/c14-11(15)10-7-5-16-8-4-2-1-3-6(8)9(7)12-13-10/h1-4H,5H2,(H,12,13)(H,14,15)

InChI Key

LCCZBCRICIYZCV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03834498

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

216.2

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.096

Distribution Coefficient, logD

-4.606

Water Solubility, LogSw

-2.16

Polar Surface Area

61.138

Acid Dissociation Constant (pKa)

1.70

Base Dissociation Constant (pKb)

-1.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

R052-2673 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anti-Aging Library (44940 compounds)

Fragments Library (11262 compounds)

Protein-Protein Interaction Library (218420 compounds)

RNA-Protein Interaction Inhibitors Library (1986 compounds)

SmartTM Library (51161 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Fragments
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with R052-2673 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound R052-2673?
Check Price and Availability of R052-2673, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of R052-2673 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for R052-2673
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for R052-2673
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of R052-2673 available by request