S022-1367 Screening compound: 2-(2-chlorophenyl)-7-(1H-indol-5-ylcarbonyl)-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one

S022-1367 Screening compound: 2-(2-chlorophenyl)-7-(1H-indol-5-ylcarbonyl)-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one
S022-1367 Screening compound: 2-(2-chlorophenyl)-7-(1H-indol-5-ylcarbonyl)-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound S022-1367
2-(2-chlorophenyl)-7-(1H-indol-5-ylcarbonyl)-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S022-1367

Molecular Formula

C24H18ClN5O2 (C24 H18 ClN5 O2)

Compound Name

2-(2-chlorophenyl)-7-(1H-indol-5-ylcarbonyl)-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one

IUPAC name

5-(2-chlorophenyl)-11-(1H-indole-5-carbonyl)-26711-tetraazatricyclo[7.4.0.0^{37}]trideca-1(9)24-trien-8-one

SMILES

O=C(c(cc1)cc2c1[nH]cc2)N(CC1)CC(C2=O)=C1N=C1N2NC(c(cccc2)c2Cl)=C1

InChI

InChI=1S/C24H18ClN5O2/c25-18-4-2-1-3-16(18)21-12-22-27-20-8-10-29(13-17(20)24(32)30(22)28-21)23(31)15-5-6-19-14(11-15)7-9-26-19/h1-7,9,11-12,26,28H,8,10,13H2

InChI Key

SACOMAFBPJAAIG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29029881

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.535

Distribution Coefficient, logD

2.533

Water Solubility, LogSw

-3.72

Polar Surface Area

66.575

Acid Dissociation Constant (pKa)

8.09

Base Dissociation Constant (pKb)

-2.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

S022-1367 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Indole Derivatives (10091 compounds)

KRAS-Targeted Library (16000 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Structure:
  • Cyclic compounds
  • Mimetics
  • Cyclic compounds
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with S022-1367 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S022-1367?
Check Price and Availability of S022-1367, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S022-1367 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S022-1367
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S022-1367
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S022-1367 available by request