S024-4392 Screening compound: 3-(4-{2-ethyl-2H,3H-imidazo[1,2-c]pyrimidin-7-yl}piperazine-1-carbonyl)-1-methyl-1H-indazole

S024-4392 Screening compound: 3-(4-{2-ethyl-2H,3H-imidazo[1,2-c]pyrimidin-7-yl}piperazine-1-carbonyl)-1-methyl-1H-indazole
S024-4392 Screening compound: 3-(4-{2-ethyl-2H,3H-imidazo[1,2-c]pyrimidin-7-yl}piperazine-1-carbonyl)-1-methyl-1H-indazole alternative view

Chemical Structure Depiction of ChemDiv screening compound S024-4392
3-(4-{2-ethyl-2H,3H-imidazo[1,2-c]pyrimidin-7-yl}piperazine-1-carbonyl)-1-methyl-1H-indazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S024-4392

Molecular Formula

C21H25N7O (C21 H25 N7 O)

Compound Name

3-(4-{2-ethyl-2H,3H-imidazo[1,2-c]pyrimidin-7-yl}piperazine-1-carbonyl)-1-methyl-1H-indazole

IUPAC name

3-(4-{2-ethyl-2H3H-imidazo[12-c]pyrimidin-7-yl}piperazine-1-carbonyl)-1-methyl-1H-indazole

SMILES

CCC(C1)N=C2N1C=NC(N(CC1)CCN1C(c1nn(C)c3c1cccc3)=O)=C2

InChI

InChI=1S/C21H25N7O/c1-3-15-13-28-14-22-18(12-19(28)23-15)26-8-10-27(11-9-26)21(29)20-16-6-4-5-7-17(16)25(2)24-20/h4-7,12,14-15H,3,8-11,13H2,1-2H3/t15-/m1/s1

InChI Key

AIRUWJJQDXGGTK-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD29028593

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.628

Distribution Coefficient, logD

-2.897

Water Solubility, LogSw

-1.98

Polar Surface Area

58.577

Acid Dissociation Constant (pKa)

28.32

Base Dissociation Constant (pKb)

11.93

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.90

S024-4392 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Targets:
  • GPCR
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S024-4392 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S024-4392?
Check Price and Availability of S024-4392, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S024-4392 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S024-4392
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S024-4392
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S024-4392 available by request