S025-0370 Screening compound: N-BENZYL-1-[(6-METHYLPYRIDIN-3-YL)CARBONYL]-1'H-SPIRO[PIPERIDINE-4,2'-PYRIDO[2,3-B]PYRAZIN]-3'-AMINE

S025-0370 Screening compound: N-BENZYL-1-[(6-METHYLPYRIDIN-3-YL)CARBONYL]-1'H-SPIRO[PIPERIDINE-4,2'-PYRIDO[2,3-B]PYRAZIN]-3'-AMINE
S025-0370 Screening compound: N-BENZYL-1-[(6-METHYLPYRIDIN-3-YL)CARBONYL]-1'H-SPIRO[PIPERIDINE-4,2'-PYRIDO[2,3-B]PYRAZIN]-3'-AMINE alternative view

Chemical Structure Depiction of ChemDiv screening compound S025-0370
N-BENZYL-1-[(6-METHYLPYRIDIN-3-YL)CARBONYL]-1'H-SPIRO[PIPERIDINE-4,2'-PYRIDO[2,3-B]PYRAZIN]-3'-AMINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S025-0370

Molecular Formula

C25H26N6O (C25 H26 N6 O)

Compound Name

N-BENZYL-1-[(6-METHYLPYRIDIN-3-YL)CARBONYL]-1'H-SPIRO[PIPERIDINE-4,2'-PYRIDO[2,3-B]PYRAZIN]-3'-AMINE

IUPAC name

n/a

SMILES

Cc(cc1)ncc1C(N(CC1)CCC11Nc(cccn2)c2N=C1NCc1ccccc1)=O

InChI

InChI=1S/C25H26N6O/c1-18-9-10-20(17-27-18)23(32)31-14-11-25(12-15-31)24(28-16-19-6-3-2-4-7-19)29-22-21(30-25)8-5-13-26-22/h2-10,13,17,30H,11-12,14-16H2,1H3,(H,26,28,29)

InChI Key

WYAGVFQONHRUFX-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.214

Distribution Coefficient, logD

0.675

Water Solubility, LogSw

-2.56

Polar Surface Area

67.252

Acid Dissociation Constant (pKa)

14.01

Base Dissociation Constant (pKb)

8.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

S025-0370 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with S025-0370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S025-0370?
Check Price and Availability of S025-0370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S025-0370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S025-0370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S025-0370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S025-0370 available by request