S026-0437 Screening compound: 3'-(benzylamino)-N-[(furan-2-yl)methyl]-1'H-spiro[piperidine-3,2'-pyrido[2,3-b]pyrazine]-1-carboxamide

S026-0437 Screening compound: 3'-(benzylamino)-N-[(furan-2-yl)methyl]-1'H-spiro[piperidine-3,2'-pyrido[2,3-b]pyrazine]-1-carboxamide
S026-0437 Screening compound: 3'-(benzylamino)-N-[(furan-2-yl)methyl]-1'H-spiro[piperidine-3,2'-pyrido[2,3-b]pyrazine]-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound S026-0437
3'-(benzylamino)-N-[(furan-2-yl)methyl]-1'H-spiro[piperidine-3,2'-pyrido[2,3-b]pyrazine]-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S026-0437

Molecular Formula

C24H26N6O2 (C24 H26 N6 O2)

Compound Name

3'-(benzylamino)-N-[(furan-2-yl)methyl]-1'H-spiro[piperidine-3,2'-pyrido[2,3-b]pyrazine]-1-carboxamide

IUPAC name

3'-(benzylamino)-N-[(furan-2-yl)methyl]-1'H-spiro[piperidine-32'-pyrido[23-b]pyrazine]-1-carboxamide

SMILES

O=C(NCc1ccco1)N(CCC1)CC11Nc(cccn2)c2N=C1NCc1ccccc1

InChI

InChI=1S/C24H26N6O2/c31-23(27-16-19-9-5-14-32-19)30-13-6-11-24(17-30)22(26-15-18-7-2-1-3-8-18)28-21-20(29-24)10-4-12-25-21/h1-5,7-10,12,14,29H,6,11,13,15-17H2,(H,27,31)(H,25,26,28)/t24-/m0/s1

InChI Key

MOVPPAZDZPWBLW-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD27643846

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.688

Distribution Coefficient, logD

0.977

Water Solubility, LogSw

-2.96

Polar Surface Area

76.134

Acid Dissociation Constant (pKa)

13.94

Base Dissociation Constant (pKb)

9.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.20

S026-0437 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

GPCR Targeted Library (31838 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Spiro Library (21655 compounds)

TLR-8 ligands Library (674 compounds)

Anti-HIV1 Library (19540 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Female
  • Skin
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
  • Kinases
  • Others
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S026-0437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S026-0437?
Check Price and Availability of S026-0437, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S026-0437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S026-0437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S026-0437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S026-0437 available by request