S214-1296 Screening compound: 1-cyclobutanecarbonyl-3-(dimethylamino)-4-phenylpiperidin-4-ol

S214-1296 Screening compound: 1-cyclobutanecarbonyl-3-(dimethylamino)-4-phenylpiperidin-4-ol
S214-1296 Screening compound: 1-cyclobutanecarbonyl-3-(dimethylamino)-4-phenylpiperidin-4-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound S214-1296
1-cyclobutanecarbonyl-3-(dimethylamino)-4-phenylpiperidin-4-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S214-1296

Molecular Formula

C18H26N2O2 (C18 H26 N2 O2)

Compound Name

1-cyclobutanecarbonyl-3-(dimethylamino)-4-phenylpiperidin-4-ol

IUPAC name

(3R4S)-1-cyclobutanecarbonyl-3-(dimethylamino)-4-phenylpiperidin-4-ol

SMILES

CN(C)[C@@H](CN(CC1)C(C2CCC2)=O)[C@@]1(c1ccccc1)O

InChI

InChI=1S/C18H26N2O2/c1-19(2)16-13-20(17(21)14-7-6-8-14)12-11-18(16,22)15-9-4-3-5-10-15/h3-5,9-10,14,16,22H,6-8,11-13H2,1-2H3/t16-,18+/m0/s1

InChI Key

NVGMNWRAOSXXPB-FUHWJXTLSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

302.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

1.402

Distribution Coefficient, logD

1.116

Water Solubility, LogSw

-1.73

Polar Surface Area

33.982

Acid Dissociation Constant (pKa)

14.99

Base Dissociation Constant (pKb)

7.37

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

61.10

S214-1296 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

CNS BBB Library (22607 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Anti-HIV1 Library (19540 compounds)

Ion Channels Focused Library (26372 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

New Agro Library (44492 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
  • Cancer
Targets:
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
Agro:
  • Agro
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with S214-1296 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S214-1296?
Check Price and Availability of S214-1296, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S214-1296 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S214-1296
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S214-1296
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S214-1296 available by request