S223-0256 Screening compound: 4-[(dimethylamino)methyl]-N~2~-(2-furylmethyl)-8-oxa-2-azaspiro[4.5]decane-2-carboxamide

S223-0256 Screening compound: 4-[(dimethylamino)methyl]-N~2~-(2-furylmethyl)-8-oxa-2-azaspiro[4.5]decane-2-carboxamide
S223-0256 Screening compound: 4-[(dimethylamino)methyl]-N~2~-(2-furylmethyl)-8-oxa-2-azaspiro[4.5]decane-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound S223-0256
4-[(dimethylamino)methyl]-N~2~-(2-furylmethyl)-8-oxa-2-azaspiro[4.5]decane-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S223-0256

Molecular Formula

C17H27N3O3 (C17 H27 N3 O3)

Compound Name

4-[(dimethylamino)methyl]-N~2~-(2-furylmethyl)-8-oxa-2-azaspiro[4.5]decane-2-carboxamide

IUPAC name

n/a

SMILES

CN(C)CC(CN(C1)C(NCc2ccco2)=O)C11CCOCC1

InChI

InChI=1S/C17H27N3O3/c1-19(2)11-14-12-20(13-17(14)5-8-22-9-6-17)16(21)18-10-15-4-3-7-23-15/h3-4,7,14H,5-6,8-13H2,1-2H3,(H,18,21)/t14-/m1/s1

InChI Key

HWJWVQGASOWVMT-CQSZACIVSA-N

MDL Number (MFCD)

MFCD29031900

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

321.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.246

Distribution Coefficient, logD

-0.807

Water Solubility, LogSw

-1.93

Polar Surface Area

46.728

Acid Dissociation Constant (pKa)

14.33

Base Dissociation Constant (pKb)

9.45

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.60

S223-0256 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S223-0256 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S223-0256?
Check Price and Availability of S223-0256, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S223-0256 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S223-0256
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S223-0256
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S223-0256 available by request