S247-0375 Screening compound: 1,2-dimethyl-1H-imidazol-4-yl [4-(methoxymethyl)-8-oxa-2-azaspiro[4.5]dec-2-yl] sulfone

S247-0375 Screening compound: 1,2-dimethyl-1H-imidazol-4-yl [4-(methoxymethyl)-8-oxa-2-azaspiro[4.5]dec-2-yl] sulfone
S247-0375 Screening compound: 1,2-dimethyl-1H-imidazol-4-yl [4-(methoxymethyl)-8-oxa-2-azaspiro[4.5]dec-2-yl] sulfone alternative view

Chemical Structure Depiction of ChemDiv screening compound S247-0375
1,2-dimethyl-1H-imidazol-4-yl [4-(methoxymethyl)-8-oxa-2-azaspiro[4.5]dec-2-yl] sulfone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S247-0375

Molecular Formula

C15H25N3O4S (C15 H25 N3 O4 S)

Compound Name

1,2-dimethyl-1H-imidazol-4-yl [4-(methoxymethyl)-8-oxa-2-azaspiro[4.5]dec-2-yl] sulfone

IUPAC name

2-[(12-dimethyl-1H-imidazol-4-yl)sulfonyl]-4-(methoxymethyl)-8-oxa-2-azaspiro[4.5]decane

SMILES

Cc1nc(S(N2CC3(CCOCC3)C(COC)C2)(=O)=O)cn1C

InChI

InChI=1S/C15H25N3O4S/c1-12-16-14(9-17(12)2)23(19,20)18-8-13(10-21-3)15(11-18)4-6-22-7-5-15/h9,13H,4-8,10-11H2,1-3H3/t13-/m0/s1

InChI Key

SVOHIKWRMDJHMF-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD29018155

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

343.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.450

Distribution Coefficient, logD

0.450

Water Solubility, LogSw

-1.34

Polar Surface Area

60.785

Acid Dissociation Constant (pKa)

27.20

Base Dissociation Constant (pKb)

1.24

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

80.00

S247-0375 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with S247-0375 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S247-0375?
Check Price and Availability of S247-0375, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S247-0375 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S247-0375
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S247-0375
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S247-0375 available by request