S272-0319 Screening compound: 4-phenyl-2-(1,4-thiazinan-4-yl)-5-pyrimidinecarboxylic acid

S272-0319 Screening compound: 4-phenyl-2-(1,4-thiazinan-4-yl)-5-pyrimidinecarboxylic acid
S272-0319 Screening compound: 4-phenyl-2-(1,4-thiazinan-4-yl)-5-pyrimidinecarboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound S272-0319
4-phenyl-2-(1,4-thiazinan-4-yl)-5-pyrimidinecarboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S272-0319

Molecular Formula

C15H15N3O2S (C15 H15 N3 O2 S)

Compound Name

4-phenyl-2-(1,4-thiazinan-4-yl)-5-pyrimidinecarboxylic acid

IUPAC name

n/a

SMILES

OC(c1c(-c2ccccc2)nc(N2CCSCC2)nc1)=O

InChI

InChI=1S/C15H15N3O2S/c19-14(20)12-10-16-15(18-6-8-21-9-7-18)17-13(12)11-4-2-1-3-5-11/h1-5,10H,6-9H2,(H,19,20)

InChI Key

VYHXVBPGQYZQGI-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

301.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.419

Distribution Coefficient, logD

1.242

Water Solubility, LogSw

-2.64

Polar Surface Area

50.618

Acid Dissociation Constant (pKa)

6.25

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

S272-0319 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with S272-0319 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S272-0319?
Check Price and Availability of S272-0319, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S272-0319 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S272-0319
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S272-0319
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S272-0319 available by request