S272-0492 Screening compound: 4-(4-methoxyphenyl)-2-(piperidin-1-yl)pyrimidine-5-carboxylic acid

S272-0492 Screening compound: 4-(4-methoxyphenyl)-2-(piperidin-1-yl)pyrimidine-5-carboxylic acid
S272-0492 Screening compound: 4-(4-methoxyphenyl)-2-(piperidin-1-yl)pyrimidine-5-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound S272-0492
4-(4-methoxyphenyl)-2-(piperidin-1-yl)pyrimidine-5-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S272-0492

Molecular Formula

C17H19N3O3 (C17 H19 N3 O3)

Compound Name

4-(4-methoxyphenyl)-2-(piperidin-1-yl)pyrimidine-5-carboxylic acid

IUPAC name

4-(4-methoxyphenyl)-2-(piperidin-1-yl)pyrimidine-5-carboxylic acid

SMILES

COc(cc1)ccc1-c(nc(N1CCCCC1)nc1)c1C(O)=O

InChI

InChI=1S/C17H19N3O3/c1-23-13-7-5-12(6-8-13)15-14(16(21)22)11-18-17(19-15)20-9-3-2-4-10-20/h5-8,11H,2-4,9-10H2,1H3,(H,21,22)

InChI Key

LLIUKTRMGMPNPC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20754839

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

313.36

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.082

Distribution Coefficient, logD

1.905

Water Solubility, LogSw

-3.04

Polar Surface Area

58.162

Acid Dissociation Constant (pKa)

6.25

Base Dissociation Constant (pKb)

7.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.30

S272-0492 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with S272-0492 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S272-0492?
Check Price and Availability of S272-0492, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S272-0492 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S272-0492
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S272-0492
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S272-0492 available by request