S324-0216 Screening compound: 4-[7-(2-furylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine

S324-0216 Screening compound: 4-[7-(2-furylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine
S324-0216 Screening compound: 4-[7-(2-furylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound S324-0216
4-[7-(2-furylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S324-0216

Molecular Formula

C18H20N4O2S (C18 H20 N4 O2 S)

Compound Name

4-[7-(2-furylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine

IUPAC name

11-[(furan-2-yl)methyl]-3-(morpholin-4-yl)-8-thia-4611-triazatricyclo[7.4.0.0^{27}]trideca-1(9)246-tetraene

SMILES

C(c1ccco1)N(CC1)Cc2c1c1c(N3CCOCC3)ncnc1s2

InChI

InChI=1S/C18H20N4O2S/c1-2-13(24-7-1)10-21-4-3-14-15(11-21)25-18-16(14)17(19-12-20-18)22-5-8-23-9-6-22/h1-2,7,12H,3-6,8-11H2

InChI Key

RORCUCNJYUNUPQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30467012

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.008

Distribution Coefficient, logD

2.997

Water Solubility, LogSw

-3.30

Polar Surface Area

43.590

Acid Dissociation Constant (pKa)

22.34

Base Dissociation Constant (pKb)

5.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.44

S324-0216 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S324-0216 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S324-0216?
Check Price and Availability of S324-0216, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S324-0216 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S324-0216
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S324-0216
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S324-0216 available by request