S324-0221 Screening compound: 4-[7-(cyclohexylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine

S324-0221 Screening compound: 4-[7-(cyclohexylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine
S324-0221 Screening compound: 4-[7-(cyclohexylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound S324-0221
4-[7-(cyclohexylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S324-0221

Molecular Formula

C20H28N4OS (C20 H28 N4 OS)

Compound Name

4-[7-(cyclohexylmethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl]morpholine

IUPAC name

11-(cyclohexylmethyl)-3-(morpholin-4-yl)-8-thia-4611-triazatricyclo[7.4.0.0^{27}]trideca-1(9)246-tetraene

SMILES

C(C1CCCCC1)N(CC1)Cc2c1c1c(N3CCOCC3)ncnc1s2

InChI

InChI=1S/C20H28N4OS/c1-2-4-15(5-3-1)12-23-7-6-16-17(13-23)26-20-18(16)19(21-14-22-20)24-8-10-25-11-9-24/h14-15H,1-13H2

InChI Key

QIZNUXRUPGILLH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996451

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.53

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.338

Distribution Coefficient, logD

4.315

Water Solubility, LogSw

-4.38

Polar Surface Area

36.034

Acid Dissociation Constant (pKa)

22.34

Base Dissociation Constant (pKb)

6.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

70.00

S324-0221 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with S324-0221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S324-0221?
Check Price and Availability of S324-0221, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S324-0221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S324-0221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S324-0221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S324-0221 available by request