S324-0373 Screening compound: 4-(4-methylpiperazino)-N~7~-propyl-5,8-dihydropyrido[4',3':4,5]thieno[2,3-d]pyrimidine-7(6H)-carboxamide

S324-0373 Screening compound: 4-(4-methylpiperazino)-N~7~-propyl-5,8-dihydropyrido[4',3':4,5]thieno[2,3-d]pyrimidine-7(6H)-carboxamide
S324-0373 Screening compound: 4-(4-methylpiperazino)-N~7~-propyl-5,8-dihydropyrido[4',3':4,5]thieno[2,3-d]pyrimidine-7(6H)-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound S324-0373
4-(4-methylpiperazino)-N~7~-propyl-5,8-dihydropyrido[4',3':4,5]thieno[2,3-d]pyrimidine-7(6H)-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S324-0373

Molecular Formula

C18H26N6OS (C18 H26 N6 OS)

Compound Name

4-(4-methylpiperazino)-N~7~-propyl-5,8-dihydropyrido[4',3':4,5]thieno[2,3-d]pyrimidine-7(6H)-carboxamide

IUPAC name

3-(4-methylpiperazin-1-yl)-N-propyl-8-thia-4611-triazatricyclo[7.4.0.0^{27}]trideca-1(9)246-tetraene-11-carboxamide

SMILES

CCCNC(N(CC1)Cc2c1c1c(N3CCN(C)CC3)ncnc1s2)=O

InChI

InChI=1S/C18H26N6OS/c1-3-5-19-18(25)24-6-4-13-14(11-24)26-17-15(13)16(20-12-21-17)23-9-7-22(2)8-10-23/h12H,3-11H2,1-2H3,(H,19,25)

InChI Key

QJBGVFXVVIGXGW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996462

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.646

Distribution Coefficient, logD

2.182

Water Solubility, LogSw

-2.81

Polar Surface Area

54.581

Acid Dissociation Constant (pKa)

16.65

Base Dissociation Constant (pKb)

7.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.10

S324-0373 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S324-0373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S324-0373?
Check Price and Availability of S324-0373, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S324-0373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S324-0373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S324-0373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S324-0373 available by request