S343-0464 Screening compound: 4-[5-(4-butoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(3,4-dimethoxyphenyl)pyrrolidin-2-one

S343-0464 Screening compound: 4-[5-(4-butoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(3,4-dimethoxyphenyl)pyrrolidin-2-one
S343-0464 Screening compound: 4-[5-(4-butoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(3,4-dimethoxyphenyl)pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound S343-0464
4-[5-(4-butoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(3,4-dimethoxyphenyl)pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S343-0464

Molecular Formula

C24H27N3O5 (C24 H27 N3 O5)

Compound Name

4-[5-(4-butoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(3,4-dimethoxyphenyl)pyrrolidin-2-one

IUPAC name

4-[5-(4-butoxyphenyl)-124-oxadiazol-3-yl]-1-(34-dimethoxyphenyl)pyrrolidin-2-one

SMILES

CCCCOc(cc1)ccc1-c1nc(C(CC2=O)CN2c(cc2)cc(OC)c2OC)no1

InChI

InChI=1S/C24H27N3O5/c1-4-5-12-31-19-9-6-16(7-10-19)24-25-23(26-32-24)17-13-22(28)27(15-17)18-8-11-20(29-2)21(14-18)30-3/h6-11,14,17H,4-5,12-13,15H2,1-3H3/t17-/m1/s1

InChI Key

LDRQSYXZFYPOHV-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD14227834

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.507

Distribution Coefficient, logD

4.507

Water Solubility, LogSw

-4.32

Polar Surface Area

71.073

Acid Dissociation Constant (pKa)

11.87

Base Dissociation Constant (pKb)

-1.09

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

S343-0464 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with S343-0464 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S343-0464?
Check Price and Availability of S343-0464, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S343-0464 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S343-0464
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S343-0464
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S343-0464 available by request