S343-1172 Screening compound: 4-[5-(1-ACETYL-4-PIPERIDYL)-1,2,4-OXADIAZOL-3-YL]-1-(2-METHOXYBENZYL)-2-PYRROLIDINONE

S343-1172 Screening compound: 4-[5-(1-ACETYL-4-PIPERIDYL)-1,2,4-OXADIAZOL-3-YL]-1-(2-METHOXYBENZYL)-2-PYRROLIDINONE
S343-1172 Screening compound: 4-[5-(1-ACETYL-4-PIPERIDYL)-1,2,4-OXADIAZOL-3-YL]-1-(2-METHOXYBENZYL)-2-PYRROLIDINONE alternative view

Chemical Structure Depiction of ChemDiv screening compound S343-1172
4-[5-(1-ACETYL-4-PIPERIDYL)-1,2,4-OXADIAZOL-3-YL]-1-(2-METHOXYBENZYL)-2-PYRROLIDINONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S343-1172

Molecular Formula

C21H26N4O4 (C21 H26 N4 O4)

Compound Name

4-[5-(1-ACETYL-4-PIPERIDYL)-1,2,4-OXADIAZOL-3-YL]-1-(2-METHOXYBENZYL)-2-PYRROLIDINONE

IUPAC name

n/a

SMILES

CC(N(CC1)CCC1c1nc(C(C2)CN(Cc(cccc3)c3OC)C2=O)no1)=O

InChI

InChI=1S/C21H26N4O4/c1-14(26)24-9-7-15(8-10-24)21-22-20(23-29-21)17-11-19(27)25(13-17)12-16-5-3-4-6-18(16)28-2/h3-6,15,17H,7-13H2,1-2H3/t17-/m1/s1

InChI Key

YRVTXWNLFPLAMA-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD28993727

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.966

Distribution Coefficient, logD

1.966

Water Solubility, LogSw

-2.25

Polar Surface Area

73.858

Acid Dissociation Constant (pKa)

13.66

Base Dissociation Constant (pKb)

-0.38

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.40

S343-1172 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Hemic and lymphatic
  • Nervous system
  • Eye
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
Targets:
  • Ion Channels
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S343-1172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S343-1172?
Check Price and Availability of S343-1172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S343-1172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S343-1172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S343-1172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S343-1172 available by request