S346-0266 Screening compound: 3-methyl-N-(3-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}phenyl)-1H-pyrazole-5-carboxamide

S346-0266 Screening compound: 3-methyl-N-(3-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}phenyl)-1H-pyrazole-5-carboxamide
S346-0266 Screening compound: 3-methyl-N-(3-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}phenyl)-1H-pyrazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound S346-0266
3-methyl-N-(3-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}phenyl)-1H-pyrazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S346-0266

Molecular Formula

C17H18N6O (C17 H18 N6 O)

Compound Name

3-methyl-N-(3-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}phenyl)-1H-pyrazole-5-carboxamide

IUPAC name

3-methyl-N-(3-{5H6H7H8H-[124]triazolo[43-a]pyridin-3-yl}phenyl)-1H-pyrazole-5-carboxamide

SMILES

Cc1n[nH]c(C(Nc2cc(-c3nnc4n3CCCC4)ccc2)=O)c1

InChI

InChI=1S/C17H18N6O/c1-11-9-14(20-19-11)17(24)18-13-6-4-5-12(10-13)16-22-21-15-7-2-3-8-23(15)16/h4-6,9-10H,2-3,7-8H2,1H3,(H,18,24)(H,19,20)

InChI Key

JASHTGLKSGWXCY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28998807

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.37

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.111

Distribution Coefficient, logD

2.108

Water Solubility, LogSw

-2.90

Polar Surface Area

70.591

Acid Dissociation Constant (pKa)

10.73

Base Dissociation Constant (pKb)

5.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

S346-0266 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Cancer
Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S346-0266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S346-0266?
Check Price and Availability of S346-0266, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S346-0266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S346-0266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S346-0266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S346-0266 available by request