S358-0272 Screening compound: 5-[6-(4-fluorophenyl)-5H,6H,8H-imidazo[4,3-c][1,4]oxazin-1-yl]-3-(thiophen-3-yl)-1,2,4-oxadiazole

S358-0272 Screening compound: 5-[6-(4-fluorophenyl)-5H,6H,8H-imidazo[4,3-c][1,4]oxazin-1-yl]-3-(thiophen-3-yl)-1,2,4-oxadiazole
S358-0272 Screening compound: 5-[6-(4-fluorophenyl)-5H,6H,8H-imidazo[4,3-c][1,4]oxazin-1-yl]-3-(thiophen-3-yl)-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound S358-0272
5-[6-(4-fluorophenyl)-5H,6H,8H-imidazo[4,3-c][1,4]oxazin-1-yl]-3-(thiophen-3-yl)-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S358-0272

Molecular Formula

C18H13FN4O2S (C18 H13 FN4 O2 S)

Compound Name

5-[6-(4-fluorophenyl)-5H,6H,8H-imidazo[4,3-c][1,4]oxazin-1-yl]-3-(thiophen-3-yl)-1,2,4-oxadiazole

IUPAC name

5-[6-(4-fluorophenyl)-5H6H8H-imidazo[43-c][14]oxazin-1-yl]-3-(thiophen-3-yl)-124-oxadiazole

SMILES

Fc1ccc(C2OCc3c(-c4nc(-c5cscc5)no4)ncn3C2)cc1

InChI

InChI=1S/C18H13FN4O2S/c19-13-3-1-11(2-4-13)15-7-23-10-20-16(14(23)8-24-15)18-21-17(22-25-18)12-5-6-26-9-12/h1-6,9-10,15H,7-8H2/t15-/m1/s1

InChI Key

INVWMWBKFWUMCN-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD29032673

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.083

Distribution Coefficient, logD

3.083

Water Solubility, LogSw

-3.13

Polar Surface Area

52.346

Acid Dissociation Constant (pKa)

22.38

Base Dissociation Constant (pKb)

0.59

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

S358-0272 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with S358-0272 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S358-0272?
Check Price and Availability of S358-0272, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S358-0272 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S358-0272
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S358-0272
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S358-0272 available by request