S372-1410 Screening compound: N-cyclooctyl-4-({1-oxo-1H,2H,7H,8H,9H,10H-pyrazino[1,2-b]indazol-2-yl}methyl)benzamide

S372-1410 Screening compound: N-cyclooctyl-4-({1-oxo-1H,2H,7H,8H,9H,10H-pyrazino[1,2-b]indazol-2-yl}methyl)benzamide
S372-1410 Screening compound: N-cyclooctyl-4-({1-oxo-1H,2H,7H,8H,9H,10H-pyrazino[1,2-b]indazol-2-yl}methyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound S372-1410
N-cyclooctyl-4-({1-oxo-1H,2H,7H,8H,9H,10H-pyrazino[1,2-b]indazol-2-yl}methyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S372-1410

Molecular Formula

C26H32N4O2 (C26 H32 N4 O2)

Compound Name

N-cyclooctyl-4-({1-oxo-1H,2H,7H,8H,9H,10H-pyrazino[1,2-b]indazol-2-yl}methyl)benzamide

IUPAC name

N-cyclooctyl-4-({1-oxo-1H2H7H8H9H10H-pyrazino[12-b]indazol-2-yl}methyl)benzamide

SMILES

O=C(c1ccc(CN(C=Cn2nc(CCCC3)c3c22)C2=O)cc1)NC1CCCCCCC1

InChI

InChI=1S/C26H32N4O2/c31-25(27-21-8-4-2-1-3-5-9-21)20-14-12-19(13-15-20)18-29-16-17-30-24(26(29)32)22-10-6-7-11-23(22)28-30/h12-17,21H,1-11,18H2,(H,27,31)

InChI Key

SVLHNCFLBSQAIQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29001706

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.663

Distribution Coefficient, logD

3.663

Water Solubility, LogSw

-3.92

Polar Surface Area

53.909

Acid Dissociation Constant (pKa)

13.41

Base Dissociation Constant (pKb)

1.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

S372-1410 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with S372-1410 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S372-1410?
Check Price and Availability of S372-1410, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S372-1410 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S372-1410
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S372-1410
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S372-1410 available by request