S375-3273 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide
Chemical Structure Depiction of ChemDiv screening compound S375-3273
N-(3-chloro-4-methoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
S375-3273
Molecular Formula
C20H20ClN5O5 (C20 H20 ClN5 O5)
Compound Name
N-(3-chloro-4-methoxyphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide
IUPAC name
N-(3-chloro-4-methoxyphenyl)-2-[4-(5-methyl-124-oxadiazol-3-yl)-13-dioxo-1H2H3H5H6H7H8H-pyrido[12-c]pyrimidin-2-yl]acetamide
SMILES
Cc1nc(C(C(N2CC(Nc(cc3)cc(Cl)c3OC)=O)=O)=C(CCCC3)N3C2=O)no1
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
445.86
Hydrogen Bond Acceptors Count
10.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
6.00
Number of Nitrogen and Oxygen Atoms
10
Partition Coefficient, logP
2.384
Distribution Coefficient, logD
2.384
Water Solubility, LogSw
-3.28
Polar Surface Area
94.333
Acid Dissociation Constant (pKa)
10.99
Base Dissociation Constant (pKb)
2.39
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
35.00
S375-3273 in Drug Discovery
Included in Screening Libraries
Antifungal Library (16415 compounds)
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
Ligand-Gated Ion Channels Library (3887 compounds)
Protein-Protein Interaction Library (218420 compounds)
Beyond the Flatland Library sp3 enriched (92988 compounds)
Inhibitors of beta-Catenin Signaling (7445 compounds)
MEF2-HDAC (class II) Modulators Library (5147 compounds)
Included in 1.7M Stock Database
- Infections
- Immune system
- animal
- Nervous system
- Eye
- Cancer
- Musculoskeletal
- Female
- Hemic and lymphatic
- Cardiovascular
- Agro
- Ion Channels
- PPI modulators
- PPI modulators
- Epigenetic
- Cyclic compounds
References: we are preparing a list of scientific research reports with S375-3273 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)