S397-0277 Screening compound: 1-(cyclopropylmethyl)-N-{2-[1-(propan-2-yl)piperidin-4-yl]ethyl}-1H,4H,6H,7H-pyrano[4,3-c]pyrazole-3-carboxamide

S397-0277 Screening compound: 1-(cyclopropylmethyl)-N-{2-[1-(propan-2-yl)piperidin-4-yl]ethyl}-1H,4H,6H,7H-pyrano[4,3-c]pyrazole-3-carboxamide
S397-0277 Screening compound: 1-(cyclopropylmethyl)-N-{2-[1-(propan-2-yl)piperidin-4-yl]ethyl}-1H,4H,6H,7H-pyrano[4,3-c]pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound S397-0277
1-(cyclopropylmethyl)-N-{2-[1-(propan-2-yl)piperidin-4-yl]ethyl}-1H,4H,6H,7H-pyrano[4,3-c]pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S397-0277

Molecular Formula

C21H34N4O2 (C21 H34 N4 O2)

Compound Name

1-(cyclopropylmethyl)-N-{2-[1-(propan-2-yl)piperidin-4-yl]ethyl}-1H,4H,6H,7H-pyrano[4,3-c]pyrazole-3-carboxamide

IUPAC name

1-(cyclopropylmethyl)-N-{2-[1-(propan-2-yl)piperidin-4-yl]ethyl}-1H4H6H7H-pyrano[43-c]pyrazole-3-carboxamide

SMILES

CC(C)N1CCC(CCNC(c2nn(CC3CC3)c3c2COCC3)=O)CC1

InChI

InChI=1S/C21H34N4O2/c1-15(2)24-10-6-16(7-11-24)5-9-22-21(26)20-18-14-27-12-8-19(18)25(23-20)13-17-3-4-17/h15-17H,3-14H2,1-2H3,(H,22,26)

InChI Key

DMCUDHCVBSXGKJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32224547

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.955

Distribution Coefficient, logD

-0.466

Water Solubility, LogSw

-2.16

Polar Surface Area

51.860

Acid Dissociation Constant (pKa)

13.34

Base Dissociation Constant (pKb)

9.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

80.95

S397-0277 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with S397-0277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S397-0277?
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What is the minimum amount of S397-0277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S397-0277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S397-0277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S397-0277 available by request