S427-0205 Screening compound: 3-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1-(propane-1-sulfonyl)piperidine

S427-0205 Screening compound: 3-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1-(propane-1-sulfonyl)piperidine
S427-0205 Screening compound: 3-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1-(propane-1-sulfonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound S427-0205
3-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1-(propane-1-sulfonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S427-0205

Molecular Formula

C17H23N3O3S (C17 H23 N3 O3 S)

Compound Name

3-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1-(propane-1-sulfonyl)piperidine

IUPAC name

3-[(5-phenyl-124-oxadiazol-3-yl)methyl]-1-(propane-1-sulfonyl)piperidine

SMILES

CCCS(N1CC(Cc2noc(-c3ccccc3)n2)CCC1)(=O)=O

InChI

InChI=1S/C17H23N3O3S/c1-2-11-24(21,22)20-10-6-7-14(13-20)12-16-18-17(23-19-16)15-8-4-3-5-9-15/h3-5,8-9,14H,2,6-7,10-13H2,1H3/t14-/m1/s1

InChI Key

UQMXZAIBKSGFJZ-CQSZACIVSA-N

MDL Number (MFCD)

MFCD29008435

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.986

Distribution Coefficient, logD

2.986

Water Solubility, LogSw

-3.29

Polar Surface Area

64.445

Acid Dissociation Constant (pKa)

22.48

Base Dissociation Constant (pKb)

-3.16

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.90

S427-0205 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

GPCR Targeted Library (31838 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Hemic and lymphatic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • Epigenetic
  • PPI modulators
  • Epigenetic
Targets:
  • GPCR
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S427-0205 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S427-0205?
Check Price and Availability of S427-0205, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S427-0205 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S427-0205
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S427-0205
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S427-0205 available by request