S434-0141 Screening compound: 4-[6-methyl-2-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyrazin-4-yl]thiomorpholine

S434-0141 Screening compound: 4-[6-methyl-2-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyrazin-4-yl]thiomorpholine
S434-0141 Screening compound: 4-[6-methyl-2-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyrazin-4-yl]thiomorpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound S434-0141
4-[6-methyl-2-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyrazin-4-yl]thiomorpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S434-0141

Molecular Formula

C16H21N5OS (C16 H21 N5 OS)

Compound Name

4-[6-methyl-2-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyrazin-4-yl]thiomorpholine

IUPAC name

4-[6-methyl-2-(pyrrolidine-1-carbonyl)pyrazolo[15-a]pyrazin-4-yl]thiomorpholine

SMILES

Cc(nc(c1c2)N3CCSCC3)cn1nc2C(N1CCCC1)=O

InChI

InChI=1S/C16H21N5OS/c1-12-11-21-14(15(17-12)19-6-8-23-9-7-19)10-13(18-21)16(22)20-4-2-3-5-20/h10-11H,2-9H2,1H3

InChI Key

PUJUGUJXVWDBDH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29005812

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

331.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.910

Distribution Coefficient, logD

1.907

Water Solubility, LogSw

-2.20

Polar Surface Area

39.828

Acid Dissociation Constant (pKa)

23.32

Base Dissociation Constant (pKb)

5.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.30

S434-0141 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS MPO Library (28609 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Nervous system
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Mechanism of action:
  • PPI modulators
  • Epigenetic
Targets:
  • Others

References: we are preparing a list of scientific research reports with S434-0141 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S434-0141?
Check Price and Availability of S434-0141, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S434-0141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S434-0141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S434-0141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S434-0141 available by request