S497-0167 Screening compound: 5-[2-(azetidin-3-yloxy)phenyl]-3-phenyl-1,2,4-oxadiazole

S497-0167 Screening compound: 5-[2-(azetidin-3-yloxy)phenyl]-3-phenyl-1,2,4-oxadiazole
S497-0167 Screening compound: 5-[2-(azetidin-3-yloxy)phenyl]-3-phenyl-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound S497-0167
5-[2-(azetidin-3-yloxy)phenyl]-3-phenyl-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S497-0167

Molecular Formula

C17H15N3O2 (C17 H15 N3 O2)

Compound Name

5-[2-(azetidin-3-yloxy)phenyl]-3-phenyl-1,2,4-oxadiazole

IUPAC name

5-[2-(azetidin-3-yloxy)phenyl]-3-phenyl-124-oxadiazole

SMILES

C1NCC1Oc(cccc1)c1-c1nc(-c2ccccc2)no1

InChI

InChI=1S/C17H15N3O2/c1-2-6-12(7-3-1)16-19-17(22-20-16)14-8-4-5-9-15(14)21-13-10-18-11-13/h1-9,13,18H,10-11H2

InChI Key

DYNMSNLAWPOVIP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28897655

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

293.33

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.144

Distribution Coefficient, logD

-0.685

Water Solubility, LogSw

-3.55

Polar Surface Area

50.338

Acid Dissociation Constant (pKa)

26.54

Base Dissociation Constant (pKb)

11.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

S497-0167 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
  • PPI modulators
Structure:
  • Fragments
  • Cyclic compounds

References: we are preparing a list of scientific research reports with S497-0167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S497-0167?
Check Price and Availability of S497-0167, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S497-0167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S497-0167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S497-0167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S497-0167 available by request